Early-life stress impairs postnatal oligodendrogenesis and adult emotional behaviour through activity-dependent mechanisms

Exposure to stress during early life (infancy/childhood) has long-term effects on the structure and function of the prefrontal cortex (PFC), and increases the risk for adult depression and anxiety disorders. However, little is known about the molecular and cellular mechanisms of these effects. Here,...

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Vydáno v:	Molecular psychiatry Ročník 25; číslo 6; s. 1159 - 1174
Hlavní autoři:	Teissier, Anne, Le Magueresse, Corentin, Olusakin, Jimmy, Andrade da Costa, Belmira L S, De Stasi, Angela M, Bacci, Alberto, Imamura Kawasawa, Yuka, Vaidya, Vidita A, Gaspar, Patricia
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Nature Publishing Group 01.06.2020
Témata:	Animal behavior Animals Anxiety disorders Behavior, Animal Cell Proliferation Children Emotional behavior Emotions Excitability Female Gene expression Genomes Immediate-early proteins Juveniles Long-term effects Male Maternal Deprivation Mice Myelin Oligodendrocytes Oligodendroglia - pathology Pattern recognition Physiology Prefrontal cortex Prefrontal Cortex - pathology Prefrontal Cortex - physiopathology Pregnancy Short term memory Stress Stress, Psychological Structure-function relationships Temporal lobe Weaning
ISSN:	1359-4184, 1476-5578, 1476-5578
On-line přístup:	Získat plný text
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