Neutrophil extracellular trap regulators in sickle cell disease: Modulation of gene expression of PADI4, neutrophil elastase, and myeloperoxidase during vaso‐occlusive crisis

Recent evidence suggests that generation of neutrophil extracellular traps (NETosis), one of the components of immunothrombosis, is associated with the pathogenesis of both venous thromboembolism and sickle cell disease (SCD). NETosis is a complex process regulated by several proteins such as peptid...

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Veröffentlicht in:	Research and practice in thrombosis and haemostasis Jg. 5; H. 1; S. 204 - 210
Hauptverfasser:	Hounkpe, Bidossessi Wilfried, Chenou, Francine, Domingos, Igor de Farias, Cardoso, Evilazio Cunha, Costa Sobreira, Marcondes José de Vasconcelos, Araujo, Aderson S., Lucena‐Araújo, Antonio Roberto, da Silva Neto, Pedro Vieira, Malheiro, Adriana, Fraiji, Nelson Abrahim, Costa, Fernando Ferreira, Bezerra, Marcos André C., Santos, Magnun Nueldo Nunes, De Paula, Erich Vinicius
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.01.2021 Elsevier Limited John Wiley and Sons Inc Elsevier
Schlagworte:	Anticoagulants Blood Blood platelets Brief Report elastase Gene expression Genotype & phenotype Granulocytes Hematology Hemoglobin Laboratories neutrophil extracellular traps Neutrophils Original ‐ Thrombosis Pathogenesis Pathogens peptidylarginine deiminase 4 Plasma Sickle cell disease Statistical analysis vaso‐occlusive crisis United States > US elastase vaso‐occlusive crisis neutrophil extracellular traps peptidylarginine deiminase 4 sickle cell disease
ISSN:	2475-0379, 2475-0379
Online-Zugang:	Volltext
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