Air Pollution (Particulate Matter) Exposure and Associations with Depression, Anxiety, Bipolar, Psychosis and Suicide Risk: A Systematic Review and Meta-Analysis
Particulate air pollution's physical health effects are well known, but associations between particulate matter (PM) exposure and mental illness have not yet been established. However, there is increasing interest in emerging evidence supporting a possible etiological link. This systematic revi...
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| Vydáno v: | Environmental health perspectives Ročník 127; číslo 12; s. 126002 |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
United States
National Institute of Environmental Health Sciences
01.12.2019
Environmental Health Perspectives |
| Témata: | |
| ISSN: | 0091-6765, 1552-9924, 1552-9924 |
| On-line přístup: | Získat plný text |
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| Shrnutí: | Particulate air pollution's physical health effects are well known, but associations between particulate matter (PM) exposure and mental illness have not yet been established. However, there is increasing interest in emerging evidence supporting a possible etiological link.
This systematic review aims to provide a comprehensive overview and synthesis of the epidemiological literature to date by investigating quantitative associations between PM and multiple adverse mental health outcomes (depression, anxiety, bipolar disorder, psychosis, or suicide).
We undertook a systematic review and meta-analysis. We searched Medline, PsycINFO, and EMBASE from January 1974 to September 2017 for English-language human observational studies reporting quantitative associations between exposure to PM
in aerodynamic diameter (ultrafine particles) and PM
and
in aerodynamic diameter (
and
, respectively) and the above psychiatric outcomes. We extracted data, appraised study quality using a published quality assessment tool, summarized methodological approaches, and conducted meta-analyses where appropriate.
Of 1,826 citations identified, 22 met our overall inclusion criteria, and we included 9 in our primary meta-analyses. In our meta-analysis of associations between long-term (
)
exposure and depression (
studies), the pooled odds ratio was 1.102 per
increase (95% CI: 1.023, 1.189;
). Two of the included studies investigating associations between long-term
exposure and anxiety also reported statistically significant positive associations, and we found a statistically significant association between short-term
exposure and suicide in meta-analysis at a 0-2 d cumulative exposure lag.
Our findings support the hypothesis of an association between long-term
exposure and depression, as well as supporting hypotheses of possible associations between long-term
exposure and anxiety and between short-term
exposure and suicide. The limited literature and methodological challenges in this field, including heterogeneous outcome definitions, exposure assessment, and residual confounding, suggest further high-quality studies are warranted to investigate potentially causal associations between air pollution and poor mental health. https://doi.org/10.1289/EHP4595. |
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| Bibliografie: | ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 14 ObjectType-Feature-3 ObjectType-Evidence Based Healthcare-1 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 |
| ISSN: | 0091-6765 1552-9924 1552-9924 |
| DOI: | 10.1289/EHP4595 |