Pan-genomic analysis of bovine monocyte-derived macrophage gene expression in response to in vitro infection with Mycobacterium avium subspecies paratuberculosis

Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne’s disease, an intestinal disease of ruminants with major economic consequences. Infectious bacilli are phagocytosed by host macrophages upon exposure where they persist, resulting in lengthy subclinical phases of infecti...

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Bibliographic Details
Published in:	Veterinary research (Paris) Vol. 43; no. 1; pp. 25 - 158
Main Authors:	MacHugh, David E, Taraktsoglou, Maria, Killick, Kate E, Nalpas, Nicolas C, Browne, John A, DE Park, Stephen, Hokamp, Karsten, Gormley, Eamonn, Magee, David A
Format:	Journal Article
Language:	English
Published:	London BioMed Central 28.03.2012 BioMed Central Ltd BMC
Subjects:	Animals apoptosis Cattle digestive system diseases Female females gene expression Gene Expression Profiling - veterinary Gene Expression Regulation Genes Genetic aspects Health aspects Host-Pathogen Interactions host-pathogen relationships hosts Immunology immunopathology Johne's disease Macrophages Macrophages - immunology Macrophages - microbiology Medicine Medicine & Public Health Microbiology Mycobacterium avium Mycobacterium avium subsp. paratuberculosis - physiology Oligonucleotide Array Sequence Analysis - veterinary paratuberculosis Paratuberculosis - genetics Paratuberculosis - immunology Paratuberculosis - microbiology Physiological aspects Polymerase Chain Reaction - veterinary Risk factors systems analysis Time Factors transcription (genetics) transcriptome transcriptomics Veterinary Medicine/Veterinary Science Virology Ireland Paratuberculosis Infection Mycobacterial Infection Mycobacterium Avium Subspecies Paratuberculosis Bovine Genome Array Cytosolic PRRs
ISSN:	1297-9716, 0928-4249, 1297-9716
Online Access:	Get full text
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