The new French 2010 Rabbit Hemorrhagic Disease Virus causes an RHD-like disease in the Sardinian Cape hare (Lepus capensis mediterraneus)

Lagovirus is an emerging genus of Caliciviridae , which includes the Rabbit Hemorrhagic Disease Virus (RHDV) of rabbits and the European brown hare syndrome virus (EBHSV) of hares that cause lethal hepatitis. In 2010, a new RHDV related virus (RHDV2) with a unique genetic and antigenic profile and l...

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Bibliographic Details
Published in:Veterinary research (Paris) Vol. 44; no. 1; pp. 96 - 307
Main Authors: Puggioni, Giantonella, Cavadini, Patrizia, Maestrale, Caterina, Scivoli, Rosario, Botti, Giuliana, Ligios, Ciriaco, Le Gall-Reculé, Ghislaine, Lavazza, Antonio, Capucci, Lorenzo
Format: Journal Article
Language:English
Published: London BioMed Central 07.10.2013
BioMed Central Ltd
Subjects:
Animals
Antibodies, Monoclonal
Antibodies, Monoclonal - blood
Antibodies, Viral
Antibodies, Viral - blood
blood
Caliciviridae Infections
Caliciviridae Infections - epidemiology
Caliciviridae Infections - genetics
Caliciviridae Infections - veterinary
Caliciviridae Infections - virology
Cytochromes b
Cytochromes b - genetics
Cytochromes b - metabolism
Diagnosis
Electron Transport Complex IV
Electron Transport Complex IV - genetics
Electron Transport Complex IV - metabolism
Enzyme-Linked Immunosorbent Assay
Enzyme-Linked Immunosorbent Assay - veterinary
epidemiology
European brown hare syndrome virus
France
Genetic aspects
genetics
Hares
Hemorrhagic Disease Virus, Rabbit
Hemorrhagic Disease Virus, Rabbit - genetics
Hemorrhagic Disease Virus, Rabbit - metabolism
Hemorrhagic Disease Virus, Rabbit - physiology
Hepatitis
Immunology
Italy
Italy - epidemiology
Lepus
Medicine
Medicine & Public Health
metabolism
Microbiology
Molecular Sequence Data
Phylogeny
physiology
Rabbit hemorrhagic disease virus
Rabbits
RNA viruses
Sardinia
Sequence Analysis, Protein
Sequence Analysis, Protein - veterinary
Short Report
veterinary
Veterinary Medicine/Veterinary Science
Viral Structural Proteins
Viral Structural Proteins - genetics
Viral Structural Proteins - metabolism
Virology
virulence
viruses
Italy
Sardinia
France
VP60 Gene
European Brown Hare Syndrome Virus
Rabbit Hemorrhagic Disease Virus
Brown Hare
Rabbit Hemorrhagic Disease
ISSN:1297-9716, 0928-4249, 1297-9716
Online Access:Get full text
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Summary:Lagovirus is an emerging genus of Caliciviridae , which includes the Rabbit Hemorrhagic Disease Virus (RHDV) of rabbits and the European brown hare syndrome virus (EBHSV) of hares that cause lethal hepatitis. In 2010, a new RHDV related virus (RHDV2) with a unique genetic and antigenic profile and lower virulence was identified in France in rabbits. Here we report the identification of RHDV2 as the cause in Sardinia of several outbreaks of acute hepatitis in rabbits and Cape hare ( Lepus capensis mediterraneus ). This is the first account of a lagovirus that causes fatal hepatitis in both rabbits and hares.
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ISSN:1297-9716
0928-4249
1297-9716
DOI:10.1186/1297-9716-44-96