Optical coherence tomography in multiple sclerosis: a systematic review and meta-analysis

Optical coherence tomography (OCT) is a new method that could aid analysis of neurodegeneration in multiple sclerosis (MS) by capturing thinning of the retinal nerve fibre layer (RNFL). Meta-analyses of data for time domain OCT show RNFL thinning of 20·38 μm (95% CI 17·91–22·86, n=2063, p<0·0001)...

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Bibliographic Details
Published in:	Lancet neurology Vol. 9; no. 9; pp. 921 - 932
Main Authors:	Petzold, Axel, de Boer, Johannes F, Schippling, Sven, Vermersch, Patrik, Kardon, Randy, Green, Ari, Calabresi, Peter A, Polman, Chris
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.09.2010 Elsevier Limited
Subjects:	Aging Algorithms Data processing Fluorescence Humans Meta-Analysis as Topic Models, Biological Multiple sclerosis Multiple Sclerosis - diagnosis Nerves Neurodegeneration Neurology Optic neuritis Retina Retina - pathology Retinal ganglion cells Reviews Segmentation Structure-function relationships Systematic review Thinning Tomography Tomography, Optical Coherence - methods
ISSN:	1474-4422, 1474-4465, 1474-4465
Online Access:	Get full text
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