Tumor-infiltrating lymphocytes: apparently good for melanoma patients. But why?

Tumor-infiltrating T lymphocytes (TILs) are observed in a number of human primary or metastatic tumors. Recently, gene expression profiling experiments suggested that the presence of T cells in metastatic melanomas before vaccinating the patients with tumor antigens could be a biomarker for clinical...

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Bibliographic Details
Published in:	Cancer Immunology, Immunotherapy Vol. 60; no. 8; pp. 1153 - 1160
Main Authors:	Cipponi, Arcadi, Wieers, Grégoire, van Baren, Nicolas, Coulie, Pierre G.
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer-Verlag 01.08.2011 Springer Springer Nature B.V
Subjects:	Animals Antigens Antigens, Neoplasm - immunology Antineoplastic agents Biological and medical sciences Biomarkers Biomarkers, Pharmacological - metabolism Biopsy Cancer Cancer Research Cancer Vaccines Dermatology Focussed Research Review Gene expression Gene Expression Profiling Humans Immunization Immunology Immunotherapy Lymphatic system Lymphocytes Lymphocytes, Tumor-Infiltrating - immunology Medical prognosis Medical research Medical sciences Medicine Medicine & Public Health Melanoma Melanoma - diagnosis Melanoma - immunology Melanoma - pathology Metastasis Multivariate analysis Neoplasm Metastasis Oncology Patient Selection Patients Pharmacology. Drug treatments Prognosis Skin Neoplasms - diagnosis Skin Neoplasms - immunology Skin Neoplasms - pathology Tumors Tumors of the skin and soft tissue. Premalignant lesions Vaccines Belgium PIVAC 10 Prognosis T lymphocyte Immunotherapy Melanoma Human Patient Tumor infiltrating lymphocyte Malignant tumor Treatment T-Lymphocyte Malignant melanoma Cancer
ISSN:	0340-7004, 1432-0851, 1432-0851
Online Access:	Get full text
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