Walking the interactome to identify human miRNA-disease associations through the functional link between miRNA targets and disease genes

Background MicroRNAs (miRNAs) are important post-transcriptional regulators that have been demonstrated to play an important role in human diseases. Elucidating the associations between miRNAs and diseases at the systematic level will deepen our understanding of the molecular mechanisms of diseases....

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Veröffentlicht in:	BMC systems biology Jg. 7; H. 1; S. 101
Hauptverfasser:	Shi, Hongbo, Xu, Juan, Zhang, Guangde, Xu, Liangde, Li, Chunquan, Wang, Li, Zhao, Zheng, Jiang, Wei, Guo, Zheng, Li, Xia
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 08.10.2013 BioMed Central Ltd
Schlagworte:	Algorithms Analysis Bioinformatics Biomedical and Life Sciences Cancer Cellular and Medical Topics Computational Biology - methods Computational Biology/Bioinformatics Disease Disease - genetics Disease susceptibility Gene expression Genetic regulation Humans Life Sciences Medical research Medicine, Experimental Methods MicroRNA MicroRNAs - genetics Nervous system diseases pharmacology and medicine Physiological Protein Interaction Mapping - methods Protein-protein interactions Proteins Regulation Research Article Simulation and Modeling Stochastic Processes Studies Systems Biology Systems physiology Random walk analysis Disease genes MiRNA-disease network MiRNA
ISSN:	1752-0509, 1752-0509
Online-Zugang:	Volltext
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