A mitochondrial root to accelerated ageing and frailty

A discovery metabolomic study was performed in a large cohort of adults to identify circulating biomarkers of frailty. The study found that carnitine and vitamin E pathways were dysregulated in frail compared with non-frail participants. These findings point to dysregulated mitochondrial metabolism...

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Vydané v:	Nature reviews. Endocrinology Ročník 16; číslo 3; s. 133 - 134
Hlavní autori:	Ferrucci, Luigi, Zampino, Marta
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Nature Publishing Group 01.03.2020
Predmet:	Aging Biomarkers - metabolism Carnitine Carnitine - metabolism Frailty Humans Metabolomics Mitochondria Mitochondria - metabolism Vitamin E Vitamin E - metabolism
ISSN:	1759-5029, 1759-5037, 1759-5037
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