A mitochondrial root to accelerated ageing and frailty

A discovery metabolomic study was performed in a large cohort of adults to identify circulating biomarkers of frailty. The study found that carnitine and vitamin E pathways were dysregulated in frail compared with non-frail participants. These findings point to dysregulated mitochondrial metabolism...

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Veröffentlicht in:	Nature reviews. Endocrinology Jg. 16; H. 3; S. 133 - 134
Hauptverfasser:	Ferrucci, Luigi, Zampino, Marta
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Nature Publishing Group 01.03.2020
Schlagworte:	Aging Biomarkers - metabolism Carnitine Carnitine - metabolism Frailty Humans Metabolomics Mitochondria Mitochondria - metabolism Vitamin E Vitamin E - metabolism
ISSN:	1759-5029, 1759-5037, 1759-5037
Online-Zugang:	Volltext
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