Fasting Imparts a Switch to Alternative Daily Pathways in Liver and Muscle

The circadian clock operates as intrinsic time-keeping machinery to preserve homeostasis in response to the changing environment. While food is a known zeitgeber for clocks in peripheral tissues, it remains unclear how lack of food influences clock function. We demonstrate that the transcriptional r...

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Bibliographic Details
Published in:	Cell reports (Cambridge) Vol. 25; no. 12; pp. 3299 - 3314.e6
Main Authors:	Kinouchi, Kenichiro, Magnan, Christophe, Ceglia, Nicholas, Liu, Yu, Cervantes, Marlene, Pastore, Nunzia, Huynh, Tuong, Ballabio, Andrea, Baldi, Pierre, Masri, Selma, Sassone-Corsi, Paolo
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 18.12.2018 Elsevier
Subjects:	Animals circadian Circadian Clocks - genetics Circadian Rhythm - physiology clock CLOCK Proteins - metabolism fasting Fasting - physiology Feeding Behavior Gene Expression Regulation liver Liver - physiology Male metabolism Mice, Inbred C57BL muscle Muscle, Skeletal - physiology Organ Specificity - genetics rhythm RNA-seq Time Factors Transcription Factors - metabolism transcriptome circadian RNA-seq liver transcriptome muscle metabolism fasting clock rhythm
ISSN:	2211-1247, 2211-1247
Online Access:	Get full text
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