Snail-overexpressing Cancer Cells Promote M2-Like Polarization of Tumor-Associated Macrophages by Delivering MiR-21-Abundant Exosomes

Epithelial-mesenchymal transition (EMT) is a major event during cancer progression and metastasis; however, the definitive role of EMT in remodeling tumor microenvironments (TMEs) is unclear. Tumor-associated macrophages (TAMs) are a major type of host immune cells in TMEs, and they perform a wide r...

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Bibliographic Details
Published in:	Neoplasia (New York, N.Y.) Vol. 20; no. 8; pp. 775 - 788
Main Authors:	Hsieh, Chia-Hsin, Tai, Shyh-Kuan, Yang, Muh-Hwa
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.08.2018 Elsevier Limited Neoplasia Press Elsevier
Subjects:	Angiogenesis Cancer CD14 antigen Colonization Exosomes Head & neck cancer Invasiveness Macrophages Mesenchyme Metastases Microenvironments Monocytes Original article Phenotypes Polarization Snail protein TAM FBS HNSCC TEX DLS ChIP EMT TEM PBMC TME
ISSN:	1476-5586, 1522-8002, 1476-5586
Online Access:	Get full text
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