The Role of IL-13, IL-15 and Granulysin in the Pathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are Severe Cutaneous Adverse Reactions (SCARS) characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. Conjunctival lesions are reported in 85% of patients. The pathogenesis of SJS/TEN/SC...

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Vydáno v:	Clinical and applied thrombosis/hemostasis Ročník 27; s. 1076029620950831
Hlavní autoři:	Sadek, Michael, Iqbal, Omer, Siddiqui, Fakiha, Till, Sean, Mazariegos, Melissa, Campbell, Edward, Mudaliar, Kumaran, Speiser, Jodi, Bontekoe, Emily, Kouta, Ahmed, Farooqui, Ambar, Daravath, Bharathi, Qneibi, Dalia, Sadek, Ramy, Hoppensteadt, Debra, Fareed, Jawed, Bouchard, Charles
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Los Angeles, CA SAGE Publications 2021 SAGE PUBLICATIONS, INC SAGE Publishing
Témata:	Antigens, Differentiation, T-Lymphocyte - blood Biomarkers - blood Biopsy Case-Control Studies Cells, Cultured Cytokines Enzyme-Linked Immunosorbent Assay Epithelium, Corneal - metabolism Fluorescent Antibody Technique Humans Interleukin-13 - blood Interleukin-15 - blood Microscopy, Fluorescence Original Pathogenesis Plasma Skin - metabolism Skin - pathology Skin diseases Stevens-Johnson Syndrome - blood Stevens-Johnson Syndrome - diagnosis Up-Regulation Stevens-Johnson syndrome granulysin IL-15 immunofluorescence microscopy IL13 toxic epidermal necrolysis
ISSN:	1076-0296, 1938-2723, 1938-2723
On-line přístup:	Získat plný text
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