Morphine is an arteriolar vasodilator in man

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • It has been recognized for about 10 years that morphine is a veno‐dilator in man and that this effect may be related to histamine release. WHAT THIS PAPER ADDS • This effect also occurs in the arteriolar system, with vasodilatation at doses of morphine that...

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Bibliographic Details
Published in:	British journal of clinical pharmacology Vol. 67; no. 4; pp. 386 - 393
Main Authors:	Afshari, Reza, Maxwell, Simon R. J., Webb, David J., Bateman, D. Nicholas
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01.04.2009 Blackwell Science Inc
Subjects:	Adult Dose-Response Relationship, Drug Forearm - blood supply histamine Histamine - pharmacology Humans Infusions, Intra-Arterial Male Middle Aged morphine Morphine - administration & dosage Morphine - pharmacology naloxone nitric oxide opioid Pharmacodynamics Plethysmography - drug effects Regional Blood Flow - drug effects Regional Blood Flow - physiology Treatment Outcome vasodilatation Vasodilation - drug effects Vasodilation - physiology Vasodilator Agents - pharmacology Young Adult
ISSN:	0306-5251, 1365-2125, 1365-2125
Online Access:	Get full text
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