Patterns of Evolution and Host Gene Mimicry in Influenza and Other RNA Viruses

It is well known that the dinucleotide CpG is under-represented in the genomic DNA of many vertebrates. This is commonly thought to be due to the methylation of cytosine residues in this dinucleotide and the corresponding high rate of deamination of 5-methycytosine, which lowers the frequency of thi...

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Vydáno v:	PLoS pathogens Ročník 4; číslo 6; s. e1000079
Hlavní autoři:	Greenbaum, Benjamin D., Levine, Arnold J., Bhanot, Gyan, Rabadan, Raul
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 06.06.2008 Public Library of Science (PLoS)
Témata:	Avian flu Biological Evolution Deoxyribonucleic acid Dinucleoside Phosphates DNA DNA methylation Evolution Genome, Human Genome, Viral Genomes Humans Immune system Infections Influenza A virus Influenza A virus - genetics Influenza B virus Influenza B virus - genetics Orthomyxoviridae - genetics Ribonucleic acid RNA RNA Viruses - genetics Selection, Genetic Swine flu Vertebrates Virology/Host Antiviral Responses Virology/Virus Evolution and Symbiosis Viruses
ISSN:	1553-7374, 1553-7366, 1553-7374
On-line přístup:	Získat plný text
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