COMT genotype and resting brain perfusion in children

Levels of extra-synaptic dopamine in the brain vary as a function of polymorphisms at the val158met locus of the catechol-O-methyltransferase ( COMT) gene. In vivo studies of this polymorphism in the human brain have typically measured patterns of neural activation during dopamine-mediated tasks in...

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Bibliographic Details
Published in:	NeuroImage (Orlando, Fla.) Vol. 48; no. 1; pp. 217 - 222
Main Authors:	Thomason, Moriah E., Waugh, Christian E., Glover, Gary H., Gotlib, Ian H.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 15.10.2009 Elsevier Limited
Subjects:	Adolescent Analysis of Variance Behavior Brain - blood supply Brain - physiology Catechol O-Methyltransferase - genetics Cerebrovascular Circulation - genetics Cerebrovascular Circulation - physiology Child Enzymes Female Genotype Genotype & phenotype Haplotypes Humans Magnetic Resonance Imaging Male Perfusion Imaging Polymorphism, Genetic Regional Blood Flow Rest Sequence Analysis, DNA Studies
ISSN:	1053-8119, 1095-9572, 1095-9572
Online Access:	Get full text
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