Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid

Diffuse gliomas are the most common malignant brain tumours in adults and include glioblastomas and World Health Organization (WHO) grade II and grade III tumours (sometimes referred to as lower-grade gliomas). Genetic tumour profiling is used to classify disease and guide therapy 1 , 2 , but involv...

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Veröffentlicht in:	Nature (London) Jg. 565; H. 7741; S. 654 - 658
Hauptverfasser:	Miller, Alexandra M., Shah, Ronak H., Pentsova, Elena I., Pourmaleki, Maryam, Briggs, Samuel, Distefano, Natalie, Zheng, Youyun, Skakodub, Anna, Mehta, Smrutiben A., Campos, Carl, Hsieh, Wan-Ying, Selcuklu, S. Duygu, Ling, Lilan, Meng, Fanli, Jing, Xiaohong, Samoila, Aliaksandra, Bale, Tejus A., Tsui, Dana W. Y., Grommes, Christian, Viale, Agnes, Souweidane, Mark M., Tabar, Viviane, Brennan, Cameron W., Reiner, Anne S., Rosenblum, Marc, Panageas, Katherine S., DeAngelis, Lisa M., Young, Robert J., Berger, Michael F., Mellinghoff, Ingo K.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 01.01.2019 Nature Publishing Group
Schlagworte:	631/1647/2217 631/67/1922 Adults Analysis Biopsy Blood circulation Brain Brain cancer Brain tumors Cancer therapies Cerebrospinal fluid Chemotherapy Chromosome deletion Consortia Deoxyribonucleic acid Development and progression Diagnosis DNA Evolution Evolution, Molecular Gene deletion Genes, Neoplasm - genetics Genome, Human - genetics Genomes Genomics Genotypes Genotyping Glioblastoma - cerebrospinal fluid Glioblastoma - genetics Glioblastoma - pathology Glioma Glioma - cerebrospinal fluid Glioma - genetics Glioma - pathology Gliomas Growth factors Humanities and Social Sciences Humans Isocitrate dehydrogenase Letter Liquid Biopsy Methods Morbidity multidisciplinary Mutation Neoplasm Grading Oncology Patients Science Science (multidisciplinary) Signal transduction Signs and symptoms Surgery Telomerase Tumorigenesis Tumors United States
ISSN:	0028-0836, 1476-4687, 1476-4687
Online-Zugang:	Volltext
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