Radiation damage to macromolecules: kill or cure?

Radiation damage induced by X‐ray beams during macromolecular diffraction experiments remains an issue of concern in structural biology. While advances in our understanding of this phenomenon, driven in part by a series of workshops in this area, undoubtedly have been and are still being made, there...

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Bibliographic Details
Published in:	Journal of synchrotron radiation Vol. 22; no. 2; pp. 195 - 200
Main Authors:	Garman, Elspeth F., Weik, Martin
Format:	Journal Article
Language:	English
Published:	5 Abbey Square, Chester, Cheshire CH1 2HU, England International Union of Crystallography 01.03.2015 John Wiley & Sons, Inc
Subjects:	Amino acids Beams (radiation) Biochemistry, Molecular Biology Computer Simulation Crystallography, X-Ray Damage Deoxyribonucleic acid Diffraction FEL Humans Life Sciences macromolecular crystallography Macromolecular Substances - radiation effects Macromolecules Models, Molecular Proteins Radiation damage Radiation Injuries radiation damage induced phasing Radioactivity SAXS Scattering, Small Angle Sensitivity and Specificity simulations Structural Biology X-Ray Diffraction - methods X-ray radiation damage X-rays FEL radiation damage induced phasing X-ray radiation damage macromolecular crystallography SAXS simulations
ISSN:	1600-5775, 0909-0495, 1600-5775
Online Access:	Get full text
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