Human Adaptation of Ebola Virus during the West African Outbreak

The 2013-2016 outbreak of Ebola virus (EBOV) in West Africa was the largest recorded. It began following the cross-species transmission of EBOV from an animal reservoir, most likely bats, into humans, with phylogenetic analysis revealing the co-circulation of several viral lineages. We hypothesized...

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Bibliographic Details
Published in:	Cell Vol. 167; no. 4; p. 1079
Main Authors:	Urbanowicz, Richard A, McClure, C Patrick, Sakuntabhai, Anavaj, Sall, Amadou A, Kobinger, Gary, Müller, Marcel A, Holmes, Edward C, Rey, Félix A, Simon-Loriere, Etienne, Ball, Jonathan K
Format:	Journal Article
Language:	English
Published:	United States 03.11.2016
Subjects:	Africa, Western - epidemiology Animals Biological Evolution Chiroptera - virology Disease Outbreaks Ebolavirus - classification Ebolavirus - genetics Ebolavirus - pathogenicity Ebolavirus - physiology Hemorrhagic Fever, Ebola - epidemiology Hemorrhagic Fever, Ebola - transmission Hemorrhagic Fever, Ebola - virology Host Specificity Humans Mutation Phylogeny Viral Envelope Proteins - genetics Viral Envelope Proteins - metabolism Zoonoses Ebola virus pseudovirus bat epistasis Makona tropism adaptation evolution human
ISSN:	1097-4172, 1097-4172
Online Access:	Get more information
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