Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides

Despite increasing evidence supporting the neuroinflammatory theory of depression, little is known about cerebral macrophages in individuals suffering from major depression. In the present study, we investigated the morphology and distribution of cells immunostained for the macrophage-specific marke...

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Bibliographic Details
Published in:	Brain, behavior, and immunity Vol. 42; pp. 50 - 59
Main Authors:	Torres-Platas, Susana G., Cruceanu, Cristiana, Chen, Gary Gang, Turecki, Gustavo, Mechawar, Naguib
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Inc 01.11.2014
Subjects:	Adult Allergy and Immunology Anterior cingulate cortex Depression Depressive Disorder - immunology Depressive Disorder - pathology Depressive Disorder - psychology Female Gyrus Cinguli - immunology Gyrus Cinguli - pathology Human Humans Macrophage Activation - immunology Macrophages - immunology Macrophages - pathology Male Microglia Microglia - immunology Microglia - pathology Middle Aged Neuroinflammation Perivascular macrophages Psychiatry Suicide Suicide - psychology White Matter - immunology White Matter - pathology Human Perivascular macrophages Anterior cingulate cortex Depression Neuroinflammation Suicide Microglia
ISSN:	0889-1591, 1090-2139, 1090-2139
Online Access:	Get full text
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