Endogenized viral sequences in mammals

•Endogenous retroviruses (ERVs) make up 25% of the genome of mammals yet sequenced.•Different ERVs are involved in placenta formation in different mammalian lineages.•ERVs can mediate resistance to closely related exogenous viruses.•ERVs modulate the innate immune system and help maintain pluripoten...

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Bibliographic Details

Published in:	Current opinion in microbiology Vol. 31; pp. 176 - 183
Main Authors:	Parrish, Nicholas F., Tomonaga, Keizo
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.06.2016
Subjects:	Adaptive Immunity - genetics Animals Endogenous Retroviruses - genetics genome Genome - genetics germ cells Humans Immunity, Innate - genetics Mammals - genetics Mammals - virology nucleotide sequences Pathology Retroviridae RNA transcription (genetics)
ISSN:	1369-5274, 1879-0364, 1879-0364
Online Access:	Get full text
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