Impact of trough IgG on pneumonia incidence in primary immunodeficiency: A meta-analysis of clinical studies

Primary immunodeficiency disease (PIDD) associated with hypogammaglobulinemia is typically treated with immunoglobulin replacement therapy. When administered as intravenous immunoglobulin (IVIG), an IgG trough occurs prior to the next replacement dose. While frequently measured, IgG trough levels re...

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Bibliographic Details
Published in:	Clinical immunology (Orlando, Fla.) Vol. 137; no. 1; pp. 21 - 30
Main Authors:	Orange, Jordan S., Grossman, William J., Navickis, Roberta J., Wilkes, Mahlon M.
Format:	Journal Article
Language:	English
Published:	Amsterdam Elsevier Inc 01.10.2010 Elsevier
Subjects:	Adolescent Adult Agammaglobulinemia - complications Agammaglobulinemia - immunology Agammaglobulinemia - prevention & control Agammaglobulinemia - therapy Aged Allergy and Immunology Biological and medical sciences Child Child, Preschool Clinical Trials as Topic Common variable immunodeficiency Dose Female Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Hypogammaglobulinemia Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunoglobulin G - blood Immunoglobulin G - immunology Immunoglobulins, Intravenous - administration & dosage Immunoglobulins, Intravenous - blood Immunoglobulins, Intravenous - therapeutic use Immunologic Deficiency Syndromes - blood Immunologic Deficiency Syndromes - complications Immunologic Deficiency Syndromes - immunology Immunologic Deficiency Syndromes - therapy Immunopathology Incidence Infant Intravenous immunoglobulin IVIG Male Medical sciences Meta-analysis Middle Aged Pneumonia Pneumonia - complications Pneumonia - immunology Pneumonia - prevention & control Primary immunodeficiency Treatment Outcome Trough concentration X-linked agammaglobulinemia Young Adult Pneumonia Trough concentration Common variable immunodeficiency Intravenous immunoglobulin IVIG X-linked agammaglobulinemia Dose Incidence Primary immunodeficiency Meta-analysis Immunopathology Lung disease Immunoglobulins Intravenous administration Respiratory disease IgG X-tinked agammaglobutinemia Concentration Epidemiology Metaanalysis Immunology Immunoglobulinopathy Primary
ISSN:	1521-6616, 1521-7035, 1521-7035
Online Access:	Get full text
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