Factor XI and XII as antithrombotic targets

Arterial and venous thrombosis are major causes of morbidity and mortality, and the incidence of thromboembolic diseases increases as a population ages. Thrombi are formed by activated platelets and fibrin. The latter is a product of the plasma coagulation system. Currently available anticoagulants...

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Bibliographic Details
Published in:	Current opinion in hematology Vol. 18; no. 5; p. 349
Main Authors:	Müller, Felicitas, Gailani, David, Renné, Thomas
Format:	Journal Article
Language:	English
Published:	United States 01.09.2011
Subjects:	Animals Anticoagulants - pharmacology Anticoagulants - therapeutic use Blood Coagulation - drug effects Blood Coagulation - physiology Factor XI - antagonists & inhibitors Factor XI - metabolism Factor XI Deficiency - blood Factor XI Deficiency - drug therapy Factor XI Deficiency - metabolism Factor XII - antagonists & inhibitors Factor XII - metabolism Factor XII Deficiency - blood Factor XII Deficiency - drug therapy Factor XII Deficiency - metabolism Hemostasis - drug effects Hemostasis - physiology Humans Thrombosis - drug therapy Thrombosis - metabolism
ISSN:	1531-7048, 1531-7048
Online Access:	Get more information
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