Antinociceptive activity of Cnicus benedictus L. leaf extract: a mechanistic evaluation

Background and purpose: Cnicus benedictus, a medicinal herb, traditionally had been used for the treatment of stomachache pain. In this study, the possible efficacy of Cnicus benedictus leaf methanolic extract (CBHE) and also cnicin, one of its major constituents, was measured on pain. Experimental...

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Bibliographic Details
Published in:	Research in pharmaceutical sciences Vol. 15; no. 5; pp. 463 - 472
Main Authors:	Ahmadimoghaddam, Davoud, Sadeghian, Reihaneh, Ranjbar, Akram, Izadidastenaei, Zohreh, Mohammadi, Saeed
Format:	Journal Article
Language:	English
Published:	Iran Wolters Kluwer - Medknow Publications 01.09.2020 Medknow Publications and Media Pvt. Ltd Wolters Kluwer - Medknow Wolters Kluwer Medknow Publications
Subjects:	Blessed thistle Chemical properties cnicin; cnicus benedictus; l-arginine/no/cgmp/k (atp); opioid receptor; peripheral antinociception Health aspects Methods Original Pain management Physiological aspects Phytochemicals Plant extracts Iran Cnicus benedictus L-arginine/NO/cGMP/K (ATP) Opioid Receptor Cnicin Peripheral antinociception
ISSN:	1735-5362, 1735-9414
Online Access:	Get full text
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