Characterization and distribution of niosomes containing ursolic acid coated with chitosan layer

Background and purpose: Ursolic acid (UA) exhibits anti-hepatocarcinoma and hepatoprotective activities, thus promising as an effective oral cancer therapy. However, its poor solubility and permeability lead to low oral bioavailability. In this study, we evaluated the effect of different ratios of S...

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Bibliographic Details
Published in:	Research in pharmaceutical sciences Vol. 16; no. 6; pp. 660 - 673
Main Authors:	Miatmoko, Andang, Safitri, Shofi, Aquila, Fayruz, Cahyani, Devy, Hariawan, Berlian, Hendrianto, Eryk, Hendradi, Esti, Sari, Retno
Format:	Journal Article
Language:	English
Published:	Iran Wolters Kluwer - Medknow Publications 01.12.2021 Medknow Publications and Media Pvt. Ltd Wolters Kluwer - Medknow Wolters Kluwer Medknow Publications
Subjects:	Antimitotic agents Antineoplastic agents biodistribution; cancer; chitosan: coumarin-6; niosomes; ursolic acid Care and treatment Chemical properties Chitin Drug delivery systems Drugs Health aspects Liver cancer Original Pharmaceutical research Terpenes Vehicles Indonesia Coumarin-6 Ursolic acid Chitosan Biodistribution Niosomes Cancer
ISSN:	1735-5362, 1735-9414
Online Access:	Get full text
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