Intra‐Articular Injection of Autologous Adipose Tissue‐Derived Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Phase IIb, Randomized, Placebo‐Controlled Clinical Trial

Mesenchymal stem cells (MSCs) have been the focus of an emerging treatment for osteoarthritis. However, few studies reported about outcomes of an intra‐articular injection of autologous adipose‐derived mesenchymal stem cells (AD‐MSCs). This study aimed to assess the efficacy and safety of a single i...

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Bibliographic Details
Published in:	Stem cells translational medicine Vol. 8; no. 6; pp. 504 - 511
Main Authors:	Lee, Woo‐Suk, Kim, Hwan Jin, Kim, Kang‐Il, Kim, Gi Beom, Jin, Wook
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01.06.2019 Oxford University Press
Subjects:	Adipose tissue Adipose Tissue - cytology Adipose‐derived mesenchymal stem cell Aged Analgesics Arthritis Autografts Body fat Cartilage diseases Cartilage, Articular - diagnostic imaging Clinical trials Double-Blind Method Drug dosages FDA approval Female Human Clinical Humans Injection Injections, Intra-Articular Intra‐articular injection Knee Laboratories Magnetic Resonance Imaging Male Mesenchymal Stem Cell Transplantation - adverse effects Mesenchymal stem cells Mesenchymal Stem Cells - cytology Mesenchymal Stem Cells - metabolism Mesenchyme Middle Aged NMR Nuclear magnetic resonance Osteoarthritis Osteoarthritis, Knee - pathology Osteoarthritis, Knee - therapy Outpatient care facilities Pain Patients Placebo Effect Stem cells Studies Transplantation, Autologous Treatment Outcome United States > US Knee Intra-articular injection Adipose-derived mesenchymal stem cell Osteoarthritis
ISSN:	2157-6564, 2157-6580, 2157-6580
Online Access:	Get full text
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