Increased frequency of CD4⁺ CD25⁺ regulatory T cells in the cerebrospinal fluid but not in the blood of multiple sclerosis patients

Naturally occurring CD4⁺ CD25⁺ regulatory T cells (nTreg) play a major role in controlling autoimmunity by suppressing self-reactive T cells. Multiple sclerosis (MS) is an inflammatory demyelinating disorder of the central nervous system (CNS), where T cells play a key role in orchestrating tissue d...

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Bibliographic Details
Published in:	Clinical and experimental immunology Vol. 147; no. 3; pp. 412 - 418
Main Authors:	Feger, U, Luther, C, Poeschel, S, Melms, A, Tolosa, E, Wiendl, H
Format:	Journal Article
Language:	English
Published:	Oxford, UK Oxford, UK : Blackwell Publishing Ltd 01.03.2007 Blackwell Publishing Ltd Blackwell Blackwell Science Inc
Subjects:	Adult Aged Aged, 80 and over Autoimmune Diseases - immunology Biological and medical sciences Cells, Cultured Clinical Studies CSF Female Forkhead Transcription Factors - cerebrospinal fluid Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immune Tolerance Immunopathology Interleukin-2 Receptor alpha Subunit - analysis Interleukin-2 Receptor alpha Subunit - blood Male Medical sciences Middle Aged multiple sclerosis Multiple Sclerosis - immunology Nervous System Diseases - immunology regulatory T cells T-Lymphocyte Subsets - immunology T-Lymphocytes, Regulatory - immunology Human Immunopathology Nervous system diseases Multiple sclerosis Helper cell Cerebrospinal fluid Blood Inflammatory disease regulatory T cells Immunology Central nervous system disease T-Lymphocyte CSF Frequency Regulatory cell
ISSN:	0009-9104, 1365-2249
Online Access:	Get full text
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