Effects of different doses of atorvastatin on human apolipoprotein B-100, B-48, and A-I metabolism

Nine hypercholesterolemic and hypertriglyceridemic subjects were enrolled in a randomized, placebo-controlled, double-blind, crossover study to test the effect of atorvastatin 20 mg/day and 80 mg/day on the kinetics of apolipoprotein B-100 (apoB-100) in triglyceride-rich lipoprotein (TRL), intermedi...

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Bibliographic Details
Published in:	Journal of lipid research Vol. 48; no. 8; pp. 1746 - 1753
Main Authors:	Lamon-Fava, Stefania, Diffenderfer, Margaret R, Barrett, P Hugh R, Buchsbaum, Aaron, Matthan, Nirupa R, Lichtenstein, Alice H, Dolnikowski, Gregory G, Horvath, Katalin, Asztalos, Bela F, Zago, Valeria, Schaefer, Ernst J
Format:	Journal Article
Language:	English
Published:	United States Elsevier 01.08.2007
Subjects:	Anticholesteremic Agents - administration & dosage Anticholesteremic Agents - pharmacology Apolipoprotein A-I - blood Apolipoprotein B-100 - blood Apolipoprotein B-48 - blood Atorvastatin campesterol Cholesterol - blood Cholesterol - metabolism Cholesterol, LDL - blood Cholesterol, LDL - metabolism Cross-Over Studies Dose-Response Relationship, Drug Female Heptanoic Acids - administration & dosage Heptanoic Acids - pharmacology Humans Kinetics lathosterol Male Middle Aged Pyrroles - administration & dosage Pyrroles - pharmacology Time Factors Triglycerides - blood Triglycerides - metabolism
ISSN:	0022-2275
Online Access:	Get full text
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