The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory

Vaccines based on mRNA-containing lipid nanoparticles (LNPs) are a promising new platform used by two leading vaccines against COVID-19. Clinical trials and ongoing vaccinations present with varying degrees of protection levels and side effects. However, the drivers of the reported side effects rema...

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Bibliographic Details
Published in:iScience Vol. 24; no. 12; p. 103479
Main Authors: Ndeupen, Sonia, Qin, Zhen, Jacobsen, Sonya, Bouteau, Aurélie, Estanbouli, Henri, Igyártó, Botond Z.
Format: Journal Article
Language:English
Published: United States Elsevier Inc 17.12.2021
Elsevier
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ISSN:2589-0042, 2589-0042
Online Access:Get full text
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