Current Contributions of Organofluorine Compounds to the Agrochemical Industry

Currently, more than 1,200 agrochemicals are listed and many of these are regularly used by farmers to generate the food supply to support the expanding global population. However, resistance to pesticides is an ever more frequently occurring phenomenon, and thus, a continuous supply of novel agroch...

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Bibliographic Details
Published in:iScience Vol. 23; no. 9; p. 101467
Main Authors: Ogawa, Yuta, Tokunaga, Etsuko, Kobayashi, Osamu, Hirai, Kenji, Shibata, Norio
Format: Journal Article
Language:English
Published: United States Elsevier Inc 25.09.2020
Elsevier
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ISSN:2589-0042, 2589-0042
Online Access:Get full text
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Summary:Currently, more than 1,200 agrochemicals are listed and many of these are regularly used by farmers to generate the food supply to support the expanding global population. However, resistance to pesticides is an ever more frequently occurring phenomenon, and thus, a continuous supply of novel agrochemicals with high efficiency, selectivity, and low toxicity is required. Moreover, the demand for a more sustainable society, by reducing the risk chemicals pose to human health and by minimizing their environmental footprint, renders the development of novel agrochemicals an ever more challenging undertaking. In the last two decades, fluoro-chemicals have been associated with significant advances in the agrochemical development process. We herein analyze the contribution that organofluorine compounds make to the agrochemical industry. Our database covers 424 fluoro-agrochemicals and is subdivided into several categories including chemotypes, mode of action, heterocycles, and chirality. This in-depth analysis reveals the unique relationship between fluorine and agrochemicals. [Display omitted] Chemistry; Industrial Chemistry; Organic Chemistry; Agricultural Science
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ISSN:2589-0042
2589-0042
DOI:10.1016/j.isci.2020.101467