Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

Biofilm formation in living organisms is associated to tissue and implant infections, and it has also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm development and being able to mimic such processes is vital for the successful development of antibiofilm treatm...

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Vydané v:iScience Ročník 24; číslo 5; s. 102443
Hlavní autori: Guzmán-Soto, Irene, McTiernan, Christopher, Gonzalez-Gomez, Mayte, Ross, Alex, Gupta, Keshav, Suuronen, Erik J., Mah, Thien-Fah, Griffith, May, Alarcon, Emilio I.
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States Elsevier Inc 21.05.2021
Elsevier
Predmet:
Microbiofilms
Microbiology
Review
Microbiology
Microbiofilms
ISSN:2589-0042, 2589-0042
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Popis
Shrnutí:Biofilm formation in living organisms is associated to tissue and implant infections, and it has also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm development and being able to mimic such processes is vital for the successful development of antibiofilm treatments and therapies. Several decades of research have contributed to building the foundation for developing in vitro and in vivo biofilm models. However, no such thing as an “all fit” in vitro or in vivo biofilm models is currently available. In this review, in addition to presenting an updated overview of biofilm formation, we critically revise recent approaches for the improvement of in vitro and in vivo biofilm models. [Display omitted] Microbiology; Microbiofilms
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ISSN:2589-0042
2589-0042
DOI:10.1016/j.isci.2021.102443