A hyaluronic acid granular hydrogel nerve guidance conduit promotes regeneration and functional recovery of injured sciatic nerves in rats

A hyaluronic acid granular hydrogel can promote neuronal and astrocyte colony formation and axonal extension in vitro, suggesting that the hydrogel can simulate an extracellular matrix structure to promote neural regeneration. However, in vivo experiments have not been conducted. In this study, we t...

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Bibliographic Details

Published in:	Neural regeneration research Vol. 18; no. 3; pp. 657 - 663
Main Authors:	Yang, Jie, Hsu, Chia-Chen, Cao, Ting-Ting, Ye, Hua, Chen, Jing, Li, Yun-Qing
Format:	Journal Article
Language:	English
Published:	India Wolters Kluwer India Pvt. Ltd 01.03.2023 Medknow Publications & Media Pvt. Ltd Department of Anatomy,College of Basic Medical Sciences,Dali University,Dali,Yunnan Province,China The Oxford Suzhou Centre for Advanced Research(OSCAR),Suzhou,Jiangsu Province,China%Department of Anatomy,Histology and Embryology&K.K.Leung Brain Research Centre,The Fourth Military Medical University,Xi'an,Shaanxi Province,China%Institute of Medical Research,Northwestern Polytechnical University,Xi'an,Shaanxi Province,China Institute of Medical Research,Northwestern Polytechnical University,Xi'an,Shaanxi Province,China%Institute of Biomedical Engineering,Department of Engineering Science,University of Oxford,Oxford,UK%Institute of Biomedical Engineering,Department of Engineering Science,University of Oxford,Oxford,UK Key Laboratory of Brain Science Research and Transformation in Tropical Environment of Hainan Province,Hainan Medical University,Haikou,Hainan Province,China Department of Anatomy,Histology and Embryology&K.K.Leung Brain Research Centre,The Fourth Military Medical University,Xi'an,Shaanxi Province,China Wolters Kluwer - Medknow Wolters Kluwer Medknow Publications
Subjects:	functional recovery; granular hydrogel; hyaluronic acid; myelin sheath; nerve conduit; nerve regeneration; peripheral nerve regeneration; sciatic nerve injury; tissue engineering; transection injury Hyaluronic acid Hydrogels Transplants & implants nerve conduit tissue engineering sciatic nerve injury granular hydrogel transection injury myelin sheath nerve regeneration peripheral nerve regeneration functional recovery hyaluronic acid
ISSN:	1673-5374, 1876-7958
Online Access:	Get full text
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