Evidence-based clinical practice guidelines for Liver Cirrhosis 2020

The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese Society of Gastroenterology (JSGE). The revised third edition was recently published in 2020. This version has become a joint guideline by the...

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Vydané v:	Journal of gastroenterology Ročník 56; číslo 7; s. 593 - 619
Hlavní autori:	Yoshiji, Hitoshi, Nagoshi, Sumiko, Akahane, Takemi, Asaoka, Yoshinari, Ueno, Yoshiyuki, Ogawa, Koji, Kawaguchi, Takumi, Kurosaki, Masayuki, Sakaida, Isao, Shimizu, Masahito, Taniai, Makiko, Terai, Shuji, Nishikawa, Hiroki, Hiasa, Yoichi, Hidaka, Hisashi, Miwa, Hiroto, Chayama, Kazuaki, Enomoto, Nobuyuki, Shimosegawa, Tooru, Takehara, Tetsuo, Koike, Kazuhiko
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Singapore Springer Singapore 01.07.2021 Springer Springer Nature B.V
Predmet:	Abdominal Surgery Antiviral agents Antiviral drugs Ascites Associations, institutions, etc Care and treatment Cirrhosis Clinical medicine Clinical practice guidelines Colorectal Surgery Evidence-based medicine Gastroenterology Hepatic encephalopathy Hepatitis B Hepatology International standards Liver cirrhosis Liver diseases Liver transplantation Medical diagnosis Medical research Medicine Medicine & Public Health Medicine, Experimental Nutrient deficiency Nutrition therapy Practice guidelines (Medicine) Pruritus Review Review Article Sarcopenia Societies Surgical Oncology Thrombocytopenia Thrombosis Transplantation of organs, tissues, etc Vitamin D Japan Treatment Diagnosis Complications Liver cirrhosis Guidelines
ISSN:	0944-1174, 1435-5922, 1435-5922
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Abstract	The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese Society of Gastroenterology (JSGE). The revised third edition was recently published in 2020. This version has become a joint guideline by the JSGE and the Japan Society of Hepatology (JSH). In addition to the clinical questions (CQs), background questions (BQs) are new items for basic clinical knowledge, and future research questions (FRQs) are newly added clinically important items. Concerning the clinical treatment of liver cirrhosis, new findings have been reported over the past 5 years since the second edition. In this revision, we decided to match the international standards as much as possible by referring to the latest international guidelines. Newly developed agents for various complications have also made great progress. In comparison with the latest global guidelines, such as the European Association for the Study of the Liver (EASL) and American Association for the Study of Liver Diseases (AASLD), we are introducing data based on the evidence for clinical practice in Japan. The flowchart for nutrition therapy was reviewed to be useful for daily medical care by referring to overseas guidelines. We also explain several clinically important items that have recently received focus and were not mentioned in the last editions. This digest version describes the issues related to the management of liver cirrhosis and several complications in clinical practice. The content begins with a diagnostic algorithm, the revised flowchart for nutritional therapy, and refracted ascites, which are of great importance to patients with cirrhosis. In addition to the updated antiviral therapy for hepatitis B and C liver cirrhosis, the latest treatments for non-viral cirrhosis, such as alcoholic steatohepatitis/non-alcoholic steatohepatitis (ASH/NASH) and autoimmune-related cirrhosis, are also described. It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, ascites, hepatorenal syndrome and acute kidney injury, hepatic encephalopathy, portal thrombus, sarcopenia, muscle cramp, thrombocytopenia, pruritus, hepatopulmonary syndrome, portopulmonary hypertension, and vitamin D deficiency, including BQ, CQ and FRQ. Finally, this guideline covers prognosis prediction and liver transplantation, especially focusing on several new findings since the last version. Since this revision is a joint guideline by both societies, the same content is published simultaneously in the official English journal of JSGE and JSH.
AbstractList	The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese Society of Gastroenterology (JSGE). The revised third edition was recently published in 2020. This version has become a joint guideline by the JSGE and the Japan Society of Hepatology (JSH). In addition to the clinical questions (CQs), background questions (BQs) are new items for basic clinical knowledge, and future research questions (FRQs) are newly added clinically important items. Concerning the clinical treatment of liver cirrhosis, new findings have been reported over the past 5 years since the second edition. In this revision, we decided to match the international standards as much as possible by referring to the latest international guidelines. Newly developed agents for various complications have also made great progress. In comparison with the latest global guidelines, such as the European Association for the Study of the Liver (EASL) and American Association for the Study of Liver Diseases (AASLD), we are introducing data based on the evidence for clinical practice in Japan. The flowchart for nutrition therapy was reviewed to be useful for daily medical care by referring to overseas guidelines. We also explain several clinically important items that have recently received focus and were not mentioned in the last editions. This digest version describes the issues related to the management of liver cirrhosis and several complications in clinical practice. The content begins with a diagnostic algorithm, the revised flowchart for nutritional therapy, and refracted ascites, which are of great importance to patients with cirrhosis. In addition to the updated antiviral therapy for hepatitis B and C liver cirrhosis, the latest treatments for non-viral cirrhosis, such as alcoholic steatohepatitis/non-alcoholic steatohepatitis (ASH/NASH) and autoimmune-related cirrhosis, are also described. It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, ascites, hepatorenal syndrome and acute kidney injury, hepatic encephalopathy, portal thrombus, sarcopenia, muscle cramp, thrombocytopenia, pruritus, hepatopulmonary syndrome, portopulmonary hypertension, and vitamin D deficiency, including BQ, CQ and FRQ. Finally, this guideline covers prognosis prediction and liver transplantation, especially focusing on several new findings since the last version. Since this revision is a joint guideline by both societies, the same content is published simultaneously in the official English journal of JSGE and JSH. The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese Society of Gastroenterology (JSGE). The revised third edition was recently published in 2020. This version has become a joint guideline by the JSGE and the Japan Society of Hepatology (JSH). In addition to the clinical questions (CQs), background questions (BQs) are new items for basic clinical knowledge, and future research questions (FRQs) are newly added clinically important items. Concerning the clinical treatment of liver cirrhosis, new findings have been reported over the past 5 years since the second edition. In this revision, we decided to match the international standards as much as possible by referring to the latest international guidelines. Newly developed agents for various complications have also made great progress. In comparison with the latest global guidelines, such as the European Association for the Study of the Liver (EASL) and American Association for the Study of Liver Diseases (AASLD), we are introducing data based on the evidence for clinical practice in Japan. The flowchart for nutrition therapy was reviewed to be useful for daily medical care by referring to overseas guidelines. We also explain several clinically important items that have recently received focus and were not mentioned in the last editions. This digest version describes the issues related to the management of liver cirrhosis and several complications in clinical practice. The content begins with a diagnostic algorithm, the revised flowchart for nutritional therapy, and refracted ascites, which are of great importance to patients with cirrhosis. In addition to the updated antiviral therapy for hepatitis B and C liver cirrhosis, the latest treatments for non-viral cirrhosis, such as alcoholic steatohepatitis/non-alcoholic steatohepatitis (ASH/NASH) and autoimmune-related cirrhosis, are also described. It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, ascites, hepatorenal syndrome and acute kidney injury, hepatic encephalopathy, portal thrombus, sarcopenia, muscle cramp, thrombocytopenia, pruritus, hepatopulmonary syndrome, portopulmonary hypertension, and vitamin D deficiency, including BQ, CQ and FRQ. Finally, this guideline covers prognosis prediction and liver transplantation, especially focusing on several new findings since the last version. Since this revision is a joint guideline by both societies, the same content is published simultaneously in the official English journal of JSGE and JSH. The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese Society of Gastroenterology (JSGE). The revised third edition was recently published in 2020. This version has become a joint guideline by the JSGE and the Japan Society of Hepatology (JSH). In addition to the clinical questions (CQs), background questions (BQs) are new items for basic clinical knowledge, and future research questions (FRQs) are newly added clinically important items. Concerning the clinical treatment of liver cirrhosis, new findings have been reported over the past 5 years since the second edition. In this revision, we decided to match the international standards as much as possible by referring to the latest international guidelines. Newly developed agents for various complications have also made great progress. In comparison with the latest global guidelines, such as the European Association for the Study of the Liver (EASL) and American Association for the Study of Liver Diseases (AASLD), we are introducing data based on the evidence for clinical practice in Japan. The flowchart for nutrition therapy was reviewed to be useful for daily medical care by referring to overseas guidelines. We also explain several clinically important items that have recently received focus and were not mentioned in the last editions. This digest version describes the issues related to the management of liver cirrhosis and several complications in clinical practice. The content begins with a diagnostic algorithm, the revised flowchart for nutritional therapy, and refracted ascites, which are of great importance to patients with cirrhosis. In addition to the updated antiviral therapy for hepatitis B and C liver cirrhosis, the latest treatments for non-viral cirrhosis, such as alcoholic steatohepatitis/non-alcoholic steatohepatitis (ASH/NASH) and autoimmune-related cirrhosis, are also described. It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, ascites, hepatorenal syndrome and acute kidney injury, hepatic encephalopathy, portal thrombus, sarcopenia, muscle cramp, thrombocytopenia, pruritus, hepatopulmonary syndrome, portopulmonary hypertension, and vitamin D deficiency, including BQ, CQ and FRQ. Finally, this guideline covers prognosis prediction and liver transplantation, especially focusing on several new findings since the last version. Since this revision is a joint guideline by both societies, the same content is published simultaneously in the official English journal of JSGE and JSH.The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese Society of Gastroenterology (JSGE). The revised third edition was recently published in 2020. This version has become a joint guideline by the JSGE and the Japan Society of Hepatology (JSH). In addition to the clinical questions (CQs), background questions (BQs) are new items for basic clinical knowledge, and future research questions (FRQs) are newly added clinically important items. Concerning the clinical treatment of liver cirrhosis, new findings have been reported over the past 5 years since the second edition. In this revision, we decided to match the international standards as much as possible by referring to the latest international guidelines. Newly developed agents for various complications have also made great progress. In comparison with the latest global guidelines, such as the European Association for the Study of the Liver (EASL) and American Association for the Study of Liver Diseases (AASLD), we are introducing data based on the evidence for clinical practice in Japan. The flowchart for nutrition therapy was reviewed to be useful for daily medical care by referring to overseas guidelines. We also explain several clinically important items that have recently received focus and were not mentioned in the last editions. This digest version describes the issues related to the management of liver cirrhosis and several complications in clinical practice. The content begins with a diagnostic algorithm, the revised flowchart for nutritional therapy, and refracted ascites, which are of great importance to patients with cirrhosis. In addition to the updated antiviral therapy for hepatitis B and C liver cirrhosis, the latest treatments for non-viral cirrhosis, such as alcoholic steatohepatitis/non-alcoholic steatohepatitis (ASH/NASH) and autoimmune-related cirrhosis, are also described. It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, ascites, hepatorenal syndrome and acute kidney injury, hepatic encephalopathy, portal thrombus, sarcopenia, muscle cramp, thrombocytopenia, pruritus, hepatopulmonary syndrome, portopulmonary hypertension, and vitamin D deficiency, including BQ, CQ and FRQ. Finally, this guideline covers prognosis prediction and liver transplantation, especially focusing on several new findings since the last version. Since this revision is a joint guideline by both societies, the same content is published simultaneously in the official English journal of JSGE and JSH.
Audience	Academic
Author	Hiasa, Yoichi Enomoto, Nobuyuki Shimizu, Masahito Nishikawa, Hiroki Taniai, Makiko Nagoshi, Sumiko Asaoka, Yoshinari Ueno, Yoshiyuki Kawaguchi, Takumi Terai, Shuji Miwa, Hiroto Shimosegawa, Tooru Hidaka, Hisashi Koike, Kazuhiko Akahane, Takemi Yoshiji, Hitoshi Chayama, Kazuaki Ogawa, Koji Sakaida, Isao Kurosaki, Masayuki Takehara, Tetsuo
Author_xml	– sequence: 1 givenname: Hitoshi surname: Yoshiji fullname: Yoshiji, Hitoshi email: yoshijih@naramed-u.ac.jp organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology, Department of Gastroenterology, Nara Medical University – sequence: 2 givenname: Sumiko surname: Nagoshi fullname: Nagoshi, Sumiko organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 3 givenname: Takemi surname: Akahane fullname: Akahane, Takemi organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 4 givenname: Yoshinari surname: Asaoka fullname: Asaoka, Yoshinari organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 5 givenname: Yoshiyuki surname: Ueno fullname: Ueno, Yoshiyuki organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 6 givenname: Koji surname: Ogawa fullname: Ogawa, Koji organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 7 givenname: Takumi surname: Kawaguchi fullname: Kawaguchi, Takumi organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 8 givenname: Masayuki surname: Kurosaki fullname: Kurosaki, Masayuki organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 9 givenname: Isao surname: Sakaida fullname: Sakaida, Isao organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 10 givenname: Masahito surname: Shimizu fullname: Shimizu, Masahito organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 11 givenname: Makiko surname: Taniai fullname: Taniai, Makiko organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 12 givenname: Shuji surname: Terai fullname: Terai, Shuji organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 13 givenname: Hiroki surname: Nishikawa fullname: Nishikawa, Hiroki organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 14 givenname: Yoichi surname: Hiasa fullname: Hiasa, Yoichi organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 15 givenname: Hisashi surname: Hidaka fullname: Hidaka, Hisashi organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 16 givenname: Hiroto surname: Miwa fullname: Miwa, Hiroto organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 17 givenname: Kazuaki surname: Chayama fullname: Chayama, Kazuaki organization: The Japan Society of Hepatology – sequence: 18 givenname: Nobuyuki surname: Enomoto fullname: Enomoto, Nobuyuki organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 19 givenname: Tooru surname: Shimosegawa fullname: Shimosegawa, Tooru organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology – sequence: 20 givenname: Tetsuo surname: Takehara fullname: Takehara, Tetsuo organization: The Japan Society of Hepatology – sequence: 21 givenname: Kazuhiko surname: Koike fullname: Koike, Kazuhiko organization: Guidelines Committee for Creating and Evaluating the “Evidence-Based Clinical Practice Guidelines for Liver Cirrhosis”, The Japanese Society of Gastroenterology / The Japan Society of Hepatology
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Snippet	The first edition of the clinical practice guidelines for liver cirrhosis was published in 2010, and the second edition was published in 2015 by the Japanese...
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SubjectTerms	Abdominal Surgery Antiviral agents Antiviral drugs Ascites Associations, institutions, etc Care and treatment Cirrhosis Clinical medicine Clinical practice guidelines Colorectal Surgery Evidence-based medicine Gastroenterology Hepatic encephalopathy Hepatitis B Hepatology International standards Liver cirrhosis Liver diseases Liver transplantation Medical diagnosis Medical research Medicine Medicine & Public Health Medicine, Experimental Nutrient deficiency Nutrition therapy Practice guidelines (Medicine) Pruritus Review Review Article Sarcopenia Societies Surgical Oncology Thrombocytopenia Thrombosis Transplantation of organs, tissues, etc Vitamin D
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Title	Evidence-based clinical practice guidelines for Liver Cirrhosis 2020
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Volume	56
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