Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damage

Patients with human papillomavirus related (HPV+) head and neck cancers (HNCs) demonstrate improved clinical outcomes compared to traditional HPV negative (HPV−) HNC patients. We have recently shown that HPV+ HNC cells are more sensitive to radiation than HPV− HNC cells. However, roles of HPV oncoge...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Radiotherapy and oncology Ročník 113; číslo 3; s. 337 - 344
Hlavní autori:	Park, Jung Wook, Nickel, Kwangok P., Torres, Alexandra D., Lee, Denis, Lambert, Paul F., Kimple, Randall J.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Ireland Elsevier B.V 01.12.2014
Predmet:	Animals Blotting, Western - methods Disease Models, Animal DNA Damage - genetics DNA damage repair DNA Repair - genetics Head and Neck Neoplasms - genetics Hematology, Oncology and Palliative Medicine HPV-positive head and neck cancer HPV16 E7 Humans Mice Mice, Transgenic Papillomaviridae - genetics Papillomavirus E7 Proteins - genetics Tumor Cells, Cultured HPV16 E7 DNA damage repair HPV-positive head and neck cancer
ISSN:	0167-8140, 1879-0887, 1879-0887
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Buďte prvý, kto okomentuje tento záznam!