Demographic Factors Associated with Presenting for Eye Evaluation in the Partnership for Research on Vaccines and Infectious Diseases in Liberia III Natural History Study of Ebola Virus Disease

PURPOSE: Survivors of Ebola virus disease (EVD) are at risk for ocular complications after infection. We sought to identify demographic factors associated with the likelihood to present for eye examination among Ebola survivors enrolled in a longitudinal natural history study of EVD. METHODS: The Pa...

Full description

Saved in:
Bibliographic Details
Published in:Middle East African journal of ophthalmology Vol. 30; no. 2; pp. 103 - 106
Main Authors: Wallace, Augustine C. D., Ross, Robin D., Tawse, Kirstin, Nyain, Ruth, Gargu, Catherine, Wentworth, Deborah E., Bishop, Rachel J., Eghrari, Allen O.
Format: Journal Article
Language:English
Published: India Wolters Kluwer - Medknow 01.04.2023
Medknow Publications and Media Pvt. Ltd
Medknow Publications & Media Pvt. Ltd
Edition:2
Subjects:
Adolescent
Adult
Aged
Child
Child, Preschool
Communicable diseases
Disease susceptibility
Ebola virus
Ebola virus infections
Ebolavirus - immunology
Eye
Eye Diseases - epidemiology
Eye examinations
Eye Infections, Viral - epidemiology
Eye Infections, Viral - virology
Female
Health aspects
Hemorrhagic Fever, Ebola - epidemiology
Hemorrhagic Fever, Ebola - prevention & control
Humans
Infectious diseases
Liberia - epidemiology
Male
Medical examination
Medical research
Medicine, Experimental
Middle Aged
Natural history
Original
Original Article
Risk Factors
Survivors
Vaccines
Young Adult
Liberia
United States
Liberia
post-ebola syndrome
Ebola
Partnership for Research on Vaccines and Infectious Diseases in Liberia
ISSN:0974-9233, 0975-1599, 0975-1599, 0974-9233
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:PURPOSE: Survivors of Ebola virus disease (EVD) are at risk for ocular complications after infection. We sought to identify demographic factors associated with the likelihood to present for eye examination among Ebola survivors enrolled in a longitudinal natural history study of EVD. METHODS: The Partnership for Research on Vaccines and Infectious Diseases in Liberia (PREVAIL) III Ebola natural history study is a 5-year study that seeks to identify long-term sequelae of EVD, including ocular sequelae. All survivors enrolled in the PREVAIL parent study from June 2015 to March 2016 were asked to return for comprehensive eye examination through June 2016. Logistic regression was conducted using self-reported survivor status, age, gender, and distance from the hospital as covariates. RESULTS: A total of 1448 subjects enrolled in the parent PREVAIL III longitudinal cohort during the defined window, of which 1375 (95.0%) followed up for baseline eye examination. Ebola survivors (635/661, 96.1%) and adult close contacts (727/767, 94.8%) demonstrated a comparable likelihood for presenting for eye examination (odds ratio [OR] 0.68, 95% confidence interval [CI] 0.36-1.28). In an adjusted model, age over 50 (OR 10.2, 95% CI 1.35-77.3) and living outside Montserrado County (OR 0.18, 95% CI 0.10-0.33) were associated with the likelihood of presenting for a baseline comprehensive eye examination. CONCLUSION: Most EVD survivors and their close contacts who enrolled during the study window presented for eye examinations. Older participants and those who lived closer to clinical facilities were most likely to present. Focused strategies accounting for these factors may assist with organizations planning survivor care in the setting of EVD.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:0974-9233
0975-1599
0975-1599
0974-9233
DOI:10.4103/meajo.meajo_53_21