Insulin-like growth factor-1 and risk of Alzheimer dementia and brain atrophy

To relate serum insulin-like growth factor-1 (IGF-1) to risk of Alzheimer disease (AD) dementia and to brain volumes in a dementia-free community sample spanning middle and older ages. Dementia-free Framingham participants from generation 1 (n = 789, age 79 ± 4 years, 64% women) and generation 2 (n...

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Bibliographic Details
Published in:	Neurology Vol. 82; no. 18; p. 1613
Main Authors:	Westwood, Andrew J, Beiser, Alexa, Decarli, Charles, Harris, Tamara B, Chen, Tai C, He, Xue-Mei, Roubenoff, Ronenn, Pikula, Aleksandra, Au, Rhoda, Braverman, Lewis E, Wolf, Philip A, Vasan, Ramachandran S, Seshadri, Sudha
Format:	Journal Article
Language:	English
Published:	United States 06.05.2014
Subjects:	Age Factors Aged Aged, 80 and over Alzheimer Disease - blood Alzheimer Disease - epidemiology Atrophy - blood Brain - pathology Female Humans Insulin-Like Growth Factor I - metabolism Magnetic Resonance Imaging Male Middle Aged Proportional Hazards Models Psychiatric Status Rating Scales Residence Characteristics Retrospective Studies Risk
ISSN:	1526-632X, 1526-632X
Online Access:	Get more information
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