Effects of intra-aortic balloon pump on in-hospital outcomes and 1-year mortality in patients with acute myocardial infarction complicated by cardiogenic shock

Background The role of intra-aortic balloon counterpulsation (IABP) in cardiogenic shock complicating acute myocardial infarction (AMI) is still a subject of intense debate. In this study, we aim to investigate the effect of IABP on the clinical outcomes of patients with AMI complicated by cardiogen...

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Veröffentlicht in:BMC cardiovascular disorders Jg. 23; H. 1; S. 1 - 7
Hauptverfasser: Fang, Dingfeng, Yu, Dongdong, Xu, Jiabin, Ma, Wei, Zhong, Yuxiang, Chen, Haibo
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London BioMed Central 29.08.2023
BioMed Central Ltd
Springer Nature B.V
BMC
Schlagworte:
Acute myocardial infarction
Analysis
Angiology
Angioplasty
Aorta
Balloon treatment
Blood Transfusion Medicine
Cardiac patients
Cardiac Surgery
Cardiogenic shock
Cardiology
Care and treatment
Cholesterol
Diabetes
Diagnosis
Evaluation
Heart attack
Heart attacks
Hemodynamics
Hypertension
Intensive care
Internal Medicine
Intra-aortic balloon pump
Medical prognosis
Medicine
Medicine & Public Health
Mortality
Myocardial infarction
Patient outcomes
Patients
Percutaneous coronary intervention
Shock
Structured Query Language-SQL
Troponin
Troponin T
Ventilators
China
United States > US
Percutaneous coronary intervention
Acute myocardial infarction
Cardiogenic shock
Mortality
Intra-aortic balloon pump
ISSN:1471-2261, 1471-2261
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Zusammenfassung:Background The role of intra-aortic balloon counterpulsation (IABP) in cardiogenic shock complicating acute myocardial infarction (AMI) is still a subject of intense debate. In this study, we aim to investigate the effect of IABP on the clinical outcomes of patients with AMI complicated by cardiogenic shock undergoing percutaneous coronary intervention (PCI). Methods From the Medical Information Mart for Intensive Care (MIMIC)-IV 2.2, 6017 AMI patients were subtracted, and 250 patients with AMI complicated by cardiogenic shock undergoing PCI were analyzed. In-hospital outcomes (death, 24-hour urine volumes, length of ICU stays, and length of hospital stays) and 1-year mortality were compared between IABP and control during the hospital course and 12-month follow-up. Results An IABP was implanted in 30.8% (77/250) of patients with infarct-related cardiogenic shock undergoing PCI. IABP patients had higher levels of Troponin T (3.94 [0.73–11.85] ng/ml vs. 1.99 [0.55–5.75] ng/ml, p -value = 0.02). IABP patients have a longer length of ICU and hospital stays (124 [63–212] hours vs. 83 [43–163] hours, p -value = 0.005; 250 [128–435] hours vs. 170 [86–294] hours, p -value = 0.009). IABP use was not associated with lower in-hospital mortality (33.8% vs. 33.0%, p -value = 0.90) and increased 24-hour urine volumes (2100 [1455–3208] ml vs. 1915 [1110–2815] ml, p -value = 0.25). In addition, 1-year mortality was not different between the IABP and the control group (48.1% vs. 48.0%; hazard ratio 1.04, 95% CI 0.70–1.54, p -value = 0.851). Conclusion IABP may be associated with longer ICU and hospital stays but not better short-and long-term clinical prognosis.
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ISSN:1471-2261
1471-2261
DOI:10.1186/s12872-023-03465-8