MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

MicroRNAs (miRNAs) are a class of small (∼22 nucleotides) noncoding RNAs involved in the regulation of gene expression at the post‐translational level. It is estimated that 30–90% of human genes are regulated by miRNAs, which makes these molecules of great importance for cell growth, activation, and...

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Vydáno v:	Glia Ročník 61; číslo 1; s. 91 - 103
Hlavní autoři:	Ponomarev, Eugene D., Veremeyko, Tatiana, Weiner, Howard L.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.01.2013 Wiley Subscription Services, Inc
Témata:	activation Animals Cell Differentiation - genetics Cell Polarity - genetics Central Nervous System - chemistry Central Nervous System - pathology Central Nervous System - physiology Central Nervous System Diseases - genetics Central Nervous System Diseases - physiopathology differentiation Humans Immunomodulation - drug effects Immunomodulation - physiology Macrophage Activation - genetics macrophages Macrophages - cytology Macrophages - pathology Macrophages - physiology microglia Microglia - physiology microRNAs MicroRNAs - administration & dosage MicroRNAs - genetics MicroRNAs - physiology myeloid cells neuroinflammation
ISSN:	0894-1491, 1098-1136, 1098-1136
On-line přístup:	Získat plný text
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