The 2nd European Carotid Surgery Trial (ECST-2): rationale and protocol for a randomised clinical trial comparing immediate revascularisation versus optimised medical therapy alone in patients with symptomatic and asymptomatic carotid stenosis at low to intermediate risk of stroke

Background Carotid endarterectomy is currently recommended for patients with recently symptomatic carotid stenosis ≥50%, based on randomised trials conducted 30 years ago. Several factors such as carotid plaque ulceration, age and associated comorbidities might influence the risk-benefit ratio of ca...

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Vydané v:	Current controlled trials in cardiovascular medicine Ročník 23; číslo 1; s. 606 - 15
Hlavní autori:	Cheng, Suk Fun, van Velzen, Twan J., Gregson, John, Richards, Toby, Jäger, Hans Rolf, Simister, Robert, Kooi, M. Eline, de Borst, Gert J., Pizzini, Francesca B., Nederkoorn, Paul J., Brown, Martin M., Bonati, Leo H.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BioMed Central 27.07.2022 BioMed Central Ltd Springer Nature B.V BMC
Predmet:	Asymptomatic Atherosclerosis Biomedicine Brain research Carotid arteries Carotid endarterectomy Carotid stenosis Carotid stenting Clinical trials Diagnosis Evaluation Health Sciences Hypotheses Ischaemic stroke Ischemia Magnetic resonance imaging Medicine Medicine & Public Health Patients Risk factors Risk prediction Statistics for Life Sciences Stenosis Stroke Stroke (Disease) Study Protocol Surgery United States United Kingdom > UK Netherlands Carotid stenosis Plaque imaging Carotid stenting Carotid endarterectomy Magnetic resonance imaging Randomised controlled trial Risk prediction Ischaemic stroke
ISSN:	1745-6215, 1745-6215
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