Long non-coding RNAs as a source of new peptides

Deep transcriptome sequencing has revealed the existence of many transcripts that lack long or conserved open reading frames (ORFs) and which have been termed long non-coding RNAs (lncRNAs). The vast majority of lncRNAs are lineage-specific and do not yet have a known function. In this study, we tes...

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Vydáno v:	eLife Ročník 3; s. e03523
Hlavní autoři:	Ruiz-Orera, Jorge, Messeguer, Xavier, Subirana, Juan Antonio, Alba, M Mar
Médium:	Journal Article Publikace
Jazyk:	angličtina
Vydáno:	England eLife Sciences Publications Ltd 16.09.2014 eLife Sciences Publications, Ltd
Témata:	Amino acids Animals Aplicacions de la informàtica Arabidopsis Bioinformàtica de novo gene evolution Disease genes Drosophila melanogaster eukaryote Evolution Evolution, Molecular Gene expression Gene Expression Profiling Genes Genomics Genomics and Evolutionary Biology Human-cells Humans Informàtica lncRNA Medical informatics Medicina Mice Open reading frames Open Reading Frames - genetics Peptides Peptides - genetics Polycistronic messenger-RNA Protein Biosynthesis Proteins Proteomics Reveals ribosome profiling Ribosomes Ribosomes - genetics Ribosomes - metabolism RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Saccaromyces-cerevisiae Saccharomyces cerevisiae Selection, Genetic Sequence Analysis, RNA Species Specificity Transcriptional landscape Zebrafish Àrees temàtiques de la UPC evolutionary biology lncRNA ribosome profiling genomics eukaryote de novo gene evolution human
ISSN:	2050-084X, 2050-084X
On-line přístup:	Získat plný text
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