Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial

The addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to cytoreductive surgery has been associated with encouraging survival results in some patients with colorectal peritoneal metastases who were eligible for complete macroscopic resection. We aimed to assess the specific benefit of add...

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Bibliographic Details
Published in:	The lancet oncology Vol. 22; no. 2; pp. 256 - 266
Main Authors:	Quénet, François, Elias, Dominique, Roca, Lise, Goéré, Diane, Ghouti, Laurent, Pocard, Marc, Facy, Olivier, Arvieux, Catherine, Lorimier, Gérard, Pezet, Denis, Marchal, Frédéric, Loi, Valeria, Meeus, Pierre, Juzyna, Beata, de Forges, Hélène, Paineau, Jacques, Glehen, Olivier, MARIANI, Pascale, BRIGAND, Cécile, BEREDER, Jean-Marc, MSIKA, Simon, PORTIER, Guillaume, RAT, Patrick
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.02.2021 Elsevier Limited Elsevier
Subjects:	5-Fluorouracil Adverse events Antigens Antineoplastic Combined Chemotherapy Protocols - administration & dosage Biomarkers Cancer Cancer therapies Chemotherapy Clinical medicine Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Colorectal Neoplasms - pathology Colorectal Neoplasms - surgery Combined Modality Therapy - adverse effects Cytoreduction Surgical Procedures Disease-Free Survival Female Fluorouracil - administration & dosage Folinic acid France Gastric cancer Hematology, Oncology, and Palliative Medicine Humans Hyperthermia Hyperthermic Intraperitoneal Chemotherapy - adverse effects Life Sciences Life span Male Medical prognosis Metastases Metastasis Middle Aged Oxaliplatin Oxaliplatin - administration & dosage Patients Peritoneal Neoplasms - drug therapy Peritoneal Neoplasms - pathology Peritoneal Neoplasms - secondary Peritoneal Neoplasms - surgery Peritoneum Surgery Survival Treatment Outcome Tumors France
ISSN:	1470-2045, 1474-5488, 1474-5488
Online Access:	Get full text
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