Increased outbreaks of monkeypox highlight gaps in actual disease burden in Sub-Saharan Africa and in animal reservoirs

•We present explanation for the 2022 monkeypox epidemic in the Western world•The true burden of MPX and the extent of animal reservoirs are not well known•The increased rodent-human interaction led to increased transmission of MPXV•The population has crossed a threshold for sustainable human-human t...

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