There is no such thing as a validated prediction model

Background Clinical prediction models should be validated before implementation in clinical practice. But is favorable performance at internal validation or one external validation sufficient to claim that a prediction model works well in the intended clinical context? Main body We argue to the cont...

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Bibliographic Details
Published in:	BMC medicine Vol. 21; no. 1; pp. 70 - 8
Main Authors:	Van Calster, Ben, Steyerberg, Ewout W., Wynants, Laure, van Smeden, Maarten
Format:	Journal Article
Language:	English
Published:	London BioMed Central 24.02.2023 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Biomarkers Biomedicine Calibration Clinical medicine Datasets Decision making Delirium Estimates External validation Fractures Health aspects Health risk assessment Heterogeneity Hospitals Internal validation Medicine Medicine & Public Health Methods Model performance Mortality Oncology Opinion Ovarian cancer Patients Populations Practice Prediction models Predictive analytics Pulmonary embolisms Risk prediction models Scanners Variables Netherlands Heterogeneity Model performance Discrimination External validation Risk prediction models Calibration Internal validation Predictive analytics
ISSN:	1741-7015, 1741-7015
Online Access:	Get full text
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