A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

Programmed cell death or apoptosis is a central biological process that is dysregulated in many diseases, including inflammatory conditions and cancer. The detection and quantification of apoptotic cells in vivo is hampered by the need for fixatives or washing steps for non-fluorogenic reagents, and...

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Veröffentlicht in:Nature communications Jg. 11; H. 1; S. 4027 - 14
Hauptverfasser: Barth, Nicole D., Subiros-Funosas, Ramon, Mendive-Tapia, Lorena, Duffin, Rodger, Shields, Mario A., Cartwright, Jennifer A., Henriques, Sónia Troeira, Sot, Jesus, Goñi, Felix M., Lavilla, Rodolfo, Marwick, John A., Vermeren, Sonja, Rossi, Adriano G., Egeblad, Mikala, Dransfield, Ian, Vendrell, Marc
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Nature Publishing Group UK 12.08.2020
Nature Publishing Group
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ISSN:2041-1723, 2041-1723
Online-Zugang:Volltext
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