A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis

Programmed cell death or apoptosis is a central biological process that is dysregulated in many diseases, including inflammatory conditions and cancer. The detection and quantification of apoptotic cells in vivo is hampered by the need for fixatives or washing steps for non-fluorogenic reagents, and...

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Vydáno v:	Nature communications Ročník 11; číslo 1; s. 4027 - 14
Hlavní autoři:	Barth, Nicole D., Subiros-Funosas, Ramon, Mendive-Tapia, Lorena, Duffin, Rodger, Shields, Mario A., Cartwright, Jennifer A., Henriques, Sónia Troeira, Sot, Jesus, Goñi, Felix M., Lavilla, Rodolfo, Marwick, John A., Vermeren, Sonja, Rossi, Adriano G., Egeblad, Mikala, Dransfield, Ian, Vendrell, Marc
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 12.08.2020 Nature Publishing Group Nature Portfolio
Témata:	13/2 13/31 14 14/19 14/34 631/80/82 639/638/11/874 Animal models Annexins Anticancer properties Apoptosis Biological activity Calcium Cell death Drug development Fixatives Humanities and Social Sciences Identification methods Medical imaging multidisciplinary Peptides Phosphatidylserine Reagents Science Science (multidisciplinary) Stains
ISSN:	2041-1723, 2041-1723
On-line přístup:	Získat plný text
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