Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study

Loss of cortical grey matter is a diagnostic marker of many neurodegenerative diseases, and is a key mediator of cognitive impairment. We postulated that cerebral amyloid angiopathy (CAA), characterised by cortical vascular amyloid deposits, is associated with cortical tissue loss independent of par...

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Bibliographic Details
Published in:	Lancet neurology Vol. 15; no. 8; pp. 811 - 819
Main Authors:	Fotiadis, Panagiotis, van Rooden, Sanneke, van der Grond, Jeroen, Schultz, Aaron, Martinez-Ramirez, Sergi, Auriel, Eitan, Reijmer, Yael, van Opstal, Anna M, Ayres, Alison, Schwab, Kristin M, Alzheimer's Disease Neuroimaging Initiative (ADNI), Hedden, Trey, Rosand, Jonathan, Viswanathan, Anand, Wermer, Marieke, Terwindt, Gisela M, Sperling, Reisa A, Polimeni, Jonathan R, Johnson, Keith A, van Buchem, Mark A, Greenberg, Steven M, Gurol, M Edip
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.07.2016 Elsevier Limited
Subjects:	Adult Age Aged Alzheimer's disease Amyloidosis - diagnostic imaging Amyloidosis - etiology Atrophy - diagnostic imaging Atrophy - etiology Case-Control Studies Cerebral Amyloid Angiopathy - complications Cerebral Amyloid Angiopathy - diagnostic imaging Cerebral Amyloid Angiopathy - genetics Cerebral Cortex - diagnostic imaging Cerebral Cortex - pathology Cerebral Hemorrhage - diagnostic imaging Cerebral Hemorrhage - etiology Cognitive ability Female Hospitals Humans Image Processing, Computer-Assisted Linear Models Magnetic Resonance Imaging Male Medical imaging Middle Aged Mutation Neurology Pathology Retrospective Studies Statistics, Nonparametric Studies
ISSN:	1474-4422, 1474-4465, 1474-4465
Online Access:	Get full text
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