Development and external validation of a faecal immunochemical test-based prediction model for colorectal cancer detection in symptomatic patients

Background Risk prediction models for colorectal cancer (CRC) detection in symptomatic patients based on available biomarkers may improve CRC diagnosis. Our aim was to develop, compare with the NICE referral criteria and externally validate a CRC prediction model, COLONPREDICT, based on clinical and...

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Bibliographic Details
Published in:	BMC medicine Vol. 14; no. 1; pp. 128 - 140
Main Authors:	Cubiella, Joaquín, Vega, Pablo, Salve, María, Díaz-Ondina, Marta, Alves, Maria Teresa, Quintero, Enrique, Álvarez-Sánchez, Victoria, Fernández-Bañares, Fernando, Boadas, Jaume, Campo, Rafel, Bujanda, Luis, Clofent, Joan, Ferrandez, Ángel, Torrealba, Leyanira, Piñol, Virginia, Rodríguez-Alcalde, Daniel, Hernández, Vicent, Fernández-Seara, Javier
Format:	Journal Article
Language:	English
Published:	London BioMed Central 31.08.2016 BioMed Central Ltd
Subjects:	Aged Biochemical markers Biomarkers - analysis Biomedicine Cancer Carcinoembryonic Antigen - analysis Colonoscopy Colonoscopy - methods Colonoscòpia Colorectal cancer Colorectal Neoplasms - diagnosis Colorectal Neoplasms - pathology Cross-Sectional Studies Càncer colorectal Diagnosis Diagnòstic Early Detection of Cancer - methods Feces Female Hemoglobins - analysis Humans Immunochemistry Immunochemistry - methods Leukocyte L1 Antigen Complex - analysis Male Marcadors bioquímics Marcadors tumorals Medical protocols Medicine Medicine & Public Health Methods Models, Theoretical Predictive Value of Tests Prognosis Pronòstic mèdic Prospective Studies Protocols clínics Research Article Risk Assessment - methods Testing Tumor markers Spain Prompt diagnosis Colonoscopy Diagnostic accuracy Colorectal cancer Faecal immunochemical test Risk stratification
ISSN:	1741-7015, 1741-7015
Online Access:	Get full text
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