Baseline-dependent improvement in CF studies, plausibility of bias

It has been commonly reported that therapeutic treatments in cystic fibrosis (CF) have ceiling effects, such that their efficacy is diminished for persons with high pre-treatment health (Montgomery et al., 2012 and Newsome et al., 2019). Floor effects have also been reported where decline is of lowe...

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Bibliographic Details
Published in:Contemporary clinical trials communications Vol. 42; p. 101378
Main Authors: Graham, Ellen, Heltshe, Sonya L., Magaret, Amalia S.
Format: Journal Article
Language:English
Published: Netherlands Elsevier Inc 01.12.2024
Elsevier
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ISSN:2451-8654, 2451-8654
Online Access:Get full text
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