Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder

Peripheral inflammation is often associated with major depressive disorder (MDD), and immunological biomarkers of depression remain a focus of investigation. We used microarray data on whole blood from two independent case-control studies of MDD: the GlaxoSmithKline–High-Throughput Disease-specific...

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Veröffentlicht in:	Biological psychiatry (1969) Jg. 83; H. 1; S. 70 - 80
Hauptverfasser:	Leday, Gwenaël G.R., Vértes, Petra E., Richardson, Sylvia, Greene, Jonathan R., Regan, Tim, Khan, Shahid, Henderson, Robbie, Freeman, Tom C., Pariante, Carmine M., Harrison, Neil A., Bullmore, Edward, Vertes, Petra, Cardinal, Rudolf, Leday, Gwenael, Freeman, Tom, Hume, David, Wu, Zhaozong, Pariante, Carmine, Cattaneo, Annamaria, Zunszain, Patricia, Borsini, Alessandra, Stewart, Robert, Chandran, David, Carvalho, Livia, Bell, Joshua, Souza-Teodoro, Luis, Perry, Hugh, Harrison, Neil, Drevets, Wayne, Wittenberg, Gayle, Jones, Declan, Stylianou, Annie, Perry, V. Hugh, Drevets, Wayne C., Wittenberg, Gayle M., Bullmore, Edward T.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.01.2018 Elsevier
Schlagworte:	Affymetrix Bayesian Biomarker Biomarkers - blood Case-Control Studies Depressive Disorder, Major - blood Depressive Disorder, Major - genetics Depressive Disorder, Major - immunology Gene Expression Gene Expression Regulation Humans Immunity, Innate - genetics Inflammation Microarray Analysis Psychiatric/Mental Health Systems Transcriptome Wernicke Encephalopathy Biomarker Inflammation Affymetrix Systems Bayesian Transcriptome
ISSN:	0006-3223, 1873-2402, 1873-2402
Online-Zugang:	Volltext
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