A linear-time algorithm for reconstructing zero-recombinant haplotype configuration on a pedigree

Background When studying genetic diseases in which genetic variations are passed on to offspring, the ability to distinguish between paternal and maternal alleles is essential. Determining haplotypes from genotype data is called haplotype inference. Most existing computational algorithms for haploty...

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Veröffentlicht in:	BMC bioinformatics Jg. 13; H. Suppl 17; S. S19
Hauptverfasser:	Lai, En-Yu, Wang, Wei-Bung, Jiang, Tao, Wu, Kun-Pin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 2012 Springer Nature B.V BMC
Schlagworte:	Algorithms Alleles Bioinformatics Biomedical and Life Sciences Child Computational Biology/Bioinformatics Computer Appl. in Life Sciences Computer applications Computer programs Computer Simulation Computers Conferences Data processing Families & family life Genetic Diseases, Inborn - genetics Genetic disorders Genetic diversity Genetic Variation Genetics Genomes Genotype Genotypes Haplotype inference Haplotypes Heredity Humans Life Sciences Mating mating loop Microarrays Models, Genetic Mutation Offspring Pedigree Proceedings Progeny Recombination, Genetic Studies zero-recombinant haplotype configuration (ZRHC) Taiwan pedigree Haplotype inference zero-recombinant haplotype configuration (ZRHC) mating loop
ISSN:	1471-2105, 1471-2105
Online-Zugang:	Volltext
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